Neurotoxicity by Cefepime: Case-Control Study
نویسندگان
چکیده
منابع مشابه
Characterizing Cefepime Neurotoxicity: A Systematic Review
Neurotoxicity due to cefepime has not been well characterized. We performed a systematic review of the literature and included 5 additional cases from our center. Of the 198 cases found, the mean age was 67 years and 87% of patients had renal dysfunction. The most common clinical features were diminished level of consciousness (80%), disorientation/agitation (47%), and myoclonus (40%). It is wo...
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Cefepime is a fourth-generation cephalosporin that is active against both gram-positive and gram-negative organisms. It is administered parenterally for the treatment of severe infections. Approximately 85% of the drug is excreted unchanged by the kidneys. Neurotoxicity in patients with renal failure who are treated with cefepime has been reported sporadically. We report on two senile patients ...
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Cefepime‐induced neurotoxicity in a pediatric patient on chronic hemodialysis: a case report
Impaired renal function increases the risk for cefepime-induced neurotoxicity. Symptoms include disorientation, myoclonus, status epilepticus, ataxia, gait disturbance, coma, and death. A high index of suspicion and early recognition of symptoms can minimize the risk of progression of symptoms to permanent neurologic impairment or death.
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ژورنال
عنوان ژورنال: Journal of Neurocritical Care
سال: 2014
ISSN: 2005-0348
DOI: 10.18700/jnc.2014.7.2.104